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Recommended Reading List

December 2004
Access Instructions:

To access the full-text articles listed in this month’s Recommended Reading List, click here to log on to the EFORT portal. Go to the section called File Cabinet, accessible through the navigation menu on your portal homepage. Here you will find a folder with the full-text articles that make up this month’s shortlist.

This month’s ‘must-read’ articles by category

Hip Osteoarthritis
"EULAR evidence based recommendations for the management of hip osteoarthritis: report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)."
Zhang W, Doherty M, Arden N, Bannworth B, Bijlsma J, Gunther K-P, et al. Annals of Rheumatic Diseases: Online First :doi: 10.1136/ard 2004.028886.

This EULAR report follows the two previous 2000 and 2003 recommendations for management of knee osteoarthritis and uses a similar evidence-based format. Unlike the ACR Recommendations in 2000, which grouped together recommendations for knee and hip OA, the EULAR OA Task Force elected to separate these two important sites of OA. Ten key propositions were developed using a Delphi technique, and the research evidence for each (efficacy, side-effects, cost effectiveness) was reviewed following a systematic review. Research evidence supported 15 of the 21 interventions included in the propositions. Interestingly, evidence specific to the hip was strikingly lacking and the strength of recommendation varied according to category or research evidence and expert opinion. This new set of recommendations raises important questions regarding management of hip OA and proposes key issues for the future research agenda. Prof Michael Doherty, Professor of Rheumatology, City Hospital, Nottingham, UK.

Ankylosing Spondylitis
"Early referral recommendations for ankylosing spondylitis (including pre-radiographic and radiographic forms) in primary care."
Sieper J, Rudwaleit M. Annals of Rheumatic Diseases: Online First :doi: 10.1136/ard.2004.028753

The diagnosis of ankylosing spondylitis is in many cases set late after onset. Because of new treatment options and the fact that early treatment seems to be beneficial it is important to try to identify these patients earlier. This paper formulates referral recommendations mainly for primary care physicians but is also of interest to musculoskeletal specialists. Dr Göran Magyar, Dept of Orthopaedic Surgery, Lund University, Sweden

COX-2 Inhibitors vs. NSAIDs
"Comparison of Lumiracoxib with Naproxen and Ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), Cardiovascular Outcomes: randomized controlled trial."
Farkouh ME, Kirshner H, Harrington RA, et al. Lancet 2004; 364: 639-640.

Recommended by Prof Daniel E Furst, Carl M Pearson Professor of Rheumatology, University of California, Los Angeles, USA.

Topical NSAIDs
"Topical NSAIDs for chronic musculoskeletal pain: systematic review and meta-analysis."
Mason L, Moore RA, Edwards JE, Derry S, McQuay HJ. BioMed Central open access: http://www.biomedcentral.com/1471-2474/5/28

A systematic review with focus on present knowledge about the efficacy of topical NSAIDs for musculoskeletal pain. The usage of topical NSAIDs is increasing not only amongst people with diagnosed musculoskeletal conditions, but also among the general population. This article gives an update and identifies gaps in the present knowledge. Dr Göran Magyar, Dept of Orthopaedic Surgery, Lund University, Sweden.

Nutritional Supplements in OA
"Effectiveness of Glucosamine for Symptoms of Knee Osteoarthritis: Results from an internet-based randomized double-blind controlled trial."
McAlindon T, Formica M, LaValley M, Lehmer M, Kabbara K. American Journal of Medicine. 2004 Nov 1;117(9):643-649.

The nutritional supplement, glucosamine sulfate, is widely used for the treatment of symptoms in patients with knee osteoarthritis based on results of systematic reviews (Cochrane collaboration, Bandolier). Furthermore, two placebo-controlled studies have demonstrated structure modification in patients with mild radiographic OA. However, this 12-week study failed to demonstrate evidence of efficacy measured by changes in the WOMAC Osteoarthritis Index. While glucosamine is safe, these results fail to support its efficacy for the treatment of symptoms in patients with knee OA. Prof Marc Hochberg, MD, MPH, University of Maryland, USA.

Spondyloarthropathies
"Biological Therapies in the Spondyloarthritides: The Current State."
Braun J, Sieper J. Rheumatology (Oxford). 2004 Sep; 43(9): 1072-1084. Epub 2004 Jun 08.

This is an extensive review, from two of the acknowledged experts in the field, of the current position on treating Spondyloarthropathies with TNF inhibitors. It covers risks and benefits, both short-term and the potential for long-term disease modification. It is well worth reading. Dr Gabrielle Kingsley, Consultant Rheumatologist, Kings College London, UK.

Simulated Surgery
"Image-Guided Surgical Simulation—A Proven Improvement."
Felländer-Tsai L, Wredmark T. Acta Orthop Scand 2004; 75 (5): 511–515.

This Guest Editorial gives a good overview of present techniques and possibilities of simulated medical education within the surgical field. It also addresses the increasing need of accountability and objectivity in high-technological medical education and training, which in a broader perspective also goes hand in hand with societies’ request of increased overall patent safety. Dr Göran Magyar, Dept of Orthopaedic Surgery, Lund University, Sweden

Total Hip Replacement
"Operating Times and Survival of Primary Total Hip Replacements: An analysis of 31745 primary cemented and uncemented total hip replacements from local hospitals reported to the Norwegian Arthroplasty Register 1987-2001."
Småbrekke A, Espehaug B, Havelin L I, Furnes O. Acta Orthop Scand 2004; 75 (5): 524-32.

Arvid Småbrekke and collegues analysed 31745 primary hip replacements from the Norwegian Arthroplasty Register and found that operating times exceeding 2.5 hours were associated with an increased risk of infection. They also found that long operating times were more common in low-volume hospitals. Dr Småbreeke says that a standardisation programme for hip arthroplasty reduced the mean operating times in his hospital from more then 3 hours in 1987 to 60 min year 2001. Prof Anders Rydholms, Professor of Orthopaedic Surgery, Lund University, Sweden.

Note: Acta Orthopaedica Scandinavica is now fully Open Access, and full text articles are immediately available at http://www.tandf.co.uk/journals/titles/00016470.asp

Reading List Access Instructions:
To access the full-text articles listed in this month’s Recommended Reading List, click here to log on to the EFORT portal. Go to the section called File Cabinet, accessible through the navigation menu on your portal homepage. Here you will find a folder with the full-text articles that make up this month’s shortlist.