EFORT EDUCATIONAL WEBINAR | NOVEMBER 2025
EFORT Webinar | CELL-FREE PRODUCTS IN OA: SECRETOM, EVS AND EXOSOMES
Monday 24 November 2025 | 19:00-20:00 CET | Free-of-charge online registration
Chair: Prof. Laura DE GIROLAMO, PhD | Director of REGAIN – REgenerative GAleazzi INstitute | Milan, Italy
Scientific Programme
The Webinar will address the following topics:
19:00-19:02 | Introduction
Prof. Laura De Girolamo, PhD | Director of REGAIN – REgenerative GAleazzi INstitute | Milan, Italy
19:02-19:17 | Tiny vesicles, big effect: exploring the basic biology of exosomes
Prof. Enrico Ragni | Galeazzi Sant’Ambrogio Hospital | Milan – Italyp
19:17-19:32 | Impact of cultivation method of mesenchymal stromal cells on the therapeutic efficacy of extracellular vesicles
Prof. Andrea De Luna | Center for Regenerative Medicine, University for Continuing Education Krems | Krems an Der Donau – Austria
19:32-19:47 | Generation EV: inheriting MSC parental potential while avoiding their clinical roadblocks
Prof. Maroun Khoury | Nano-regenerative Laboratory, Biomedical Investigastion and Innovation Center (CiiB) University de los Andes | Santiago, Chile
19:47-19:58 | Questions and Answers | All Webinar audience
19:58-20:00 | Final Remarks | Prof. Laura De Girolamo, PhD | Milan, Italy
Learning Objectives
The Next Horizon in Orthobiologics: Moving Beyond the Cell.
Join us for a definitive session bridging the lab bench and the bedside. This webinar will analyze the cutting-edge science and emerging clinical application of cell-free therapeutics for Osteoarthritis (OA)—the most promising area of musculoskeletal regeneration.
By the end of this webinar, participants will be able to:
Understand Exosome Fundamentals and Mechanisms
- Explain the basic biology of exosomes (“Tiny vesicles, big effect”), including their origin, composition, and role as key mediators in cell-to-cell communication.
- Articulate the specific mechanisms by which exosomes exert their therapeutic effects (e.g., anti-inflammatory, regenerative) in the context of joint disease.
Analyse Production and Potency Factors
- Evaluate the significant impact of mesenchymal stromal cell (MSC) cultivation methods on the quantity, quality, and resultant therapeutic efficacy of their derived Extracellular Vesicles (EVs).
- Identify the critical production variables that researchers and developers must control to ensure consistent and potent cell-free OA biotherapeutics.
Assess Clinical and Safety Data
- Appraise the current scientific and clinical evidence regarding the safety and efficacy of exosome biotherapeutics specifically for the treatment of joint disease.
- Discuss the major challenges and considerations necessary for the clinical translation of exosome-based therapies, including regulatory pathways and safety monitoring in patients.
This EFORT Educational Webinar is organised by EFORT independent of any commercial educational support.
UPCOMING EFORT WEBINARS
For more information on our EFORT Webinars, please contact webinars@efort.org.
| Date/Time | Event | Category |
|---|---|---|
| 24 November 2025 | EFORT Webinar | Cell-free products in OA: secretome, Evs and exosomes | |
It is EFORT’s aim to promote the exchange of scientific knowledge and experience in the field of prevention and both the conservative and surgical treatment of diseases and injuries concerning the musculo-skeletal system. A particular emphasis is placed upon activities focusing on education and research.
The EFORT Education Committee and its subgroups are dedicated to develop our live webinar programmes which are scheduled to take place on the last Monday of the month.
For more information on our EFORT Webinars, please contact webinars@efort.org.
EFORT WEBINARS 2025
AVAILABLE ONLINE REPLAYS
EFORT Webinar | DISTAL FEMUR FRACTURE. RETROGRADE NAILING vs. LOCKING PLATE
Monday 27 October 2025 | 19:00-20:00 CET | Webinar REPLAY available
More information
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- Scientific Programme & Faculty | PDF Document | 1 page | 175 kb
EFORT Webinar | BONE LOSS MANAGEMENT IN REVISION HIP REPLACEMENT
Monday 29 September 2025 | Webinar REPLAY available
More information
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- Scientific Programme & Faculty | PDF Document | 1 page | 175 kb
EFORT Webinar | LATEST ADVANCES AND EVIDENCE IN ROBOTIC ORTHOPAEDIC SURGERY
Monday 30 June 2025 | Webinar REPLAY available
More information
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- Scientific Programme & Faculty | PDF Document | 1 page | 175 kb
EFORT Webinar | CONTEMPORARY CONCEPTS IN ANKLE FRACTURE SURGICAL MANAGEMENT
Monday 26 May 2025 | Webinar REPLAY available
More information
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- Scientific Programme & Faculty | PDF Document | 1 page | 200 kb
EFORT Webinar | THORACOLUMBAR VERTEBRAL FRACTURES
Monday 28 April 2025 | Webinar REPLAY available
More information
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- Scientific Programme & Faculty | PDF Document | 1 page | 180 kb
EFORT Webinar | NEXT-GENERATION APPROACHES TO PERIPROSTHETIC JOINT INFECTIONS
Monday 31 March 2025 | Webinar REPLAY available
More information
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- Scientific Programme & Faculty | PDF Document | 1 page | 230 kb
EFORT Webinar | INNOVATION IN PERIPROSTHETIC FRACTURES
Monday 24 February 2025 | Webinar REPLAY available
More information
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- Scientific Programme & Faculty | PDF Document | 1 page | 180 kb
EFORT Webinar | ANTERIOR SHOULDER INSTABILITY IN PROFESSIONAL ATHLETES
Monday 27 January 2025 | Webinar REPLAY available
More information
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- Scientific Programme & Faculty | PDF Document | 1 page | 210 kb
EFORT WEBINARS 2024
AVAILABLE ONLINE REPLAYS
EFORT Webinar | MANAGEMENT OPTIONS FOR ACUTE PROSTHETIC JOINT INFECTIONS
Monday 25 November 2024 | Webinar REPLAY available
More information
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- Scientific Programme & Faculty | PDF Document | 1 page | 170 kb
EFORT Webinar | ADVANCEMENTS IN CARTILAGE REPAIR: FROM MOLECULES AND CELLS TO CLINICAL STRATEGIES | Monday 28 October 2024 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 160 kb
EFORT Webinar | SURGICAL APPROACHES FOR ACETABULAR FRACTURE FIXATION: WHICH ONE; WHEN AND WHY | Monday 30 September 2024 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 200 kb
EFORT Webinar | SHORT-TERM COMPLICATIONS OF DISTAL RADIUS FRACTURE (infection excluded)
Monday 24 June 2024 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 190 kb
EFORT Webinar | OSSEOINTEGRATION OF ORTHOPAEDIC IMPLANTS
Monday 13 May 2024 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 190 kb
EFORT Webinar | ACETABULAR FRACTURE MANAGEMENT IN THE ELDERLY: FIX OR REPLACE?
Monday 22 April 2024 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 170 kb
EFORT Webinar | INSTABILITY IN TOTAL HIP ARTHROPLASTY
Monday 25 March 2024 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 180 kb
EFORT Webinar | IMPLANTABLES & SMART IMPLANTS: READY FOR CLINIC !?
Monday 26 February 2024 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 176 kb
EFORT Webinar | LIMITS OF THE MASQUELET TECHNIQUE IN SEGMENTAL BONE DEFECTS
Monday 29 January 2024 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 170 kb
EFORT WEBINARS 2023
AVAILABLE ONLINE REPLAYS
EFORT Webinar | TIBIAL PLATEAU FRACTURES MANAGEMENT
Monday 27 November 2023 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 210 kb
EFORT Webinar | DEGENERATIVE SPONDYLOLISTHESIS
Monday 30 October 2023 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 210 kb
EFORT Webinar | CEMENT REVISITED
Monday 25 September 2023 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 200 kb
EFORT Webinar | SOFT TISSUE SARCOMAS TREATMENT: AN UPDATE
Monday 26 June 2023 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 192 kb
EFORT / ESTES Webinar | FRACTURES AROUND THE ELBOW: FLOATING ELBOW INJURIES
Monday 24 April 2023 | Webinar REPLAY available
More information
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- Scientific Programme & Faculty | PDF Document | 1 page | 136 kb
EFORT Webinar | LOWER LIMB DEFORMITY CORRECTION
Monday 27 March 2023 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 190 kb
EFORT Webinar | DIGITAL ORTHOPAEDICS II: WEARABLES & APPS
Monday 27 February 2023 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 210 kb
EFORT Webinar | FLOATING KNEE INJURIES
Monday 30 January 2023 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 190 kb
EFORT WEBINARS 2022
AVAILABLE ONLINE REPLAYS
EFORT Webinar | NECK OF FEMUR FRACTURE IN THE YOUNG ADULT
Monday 28 November 2022 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 190 kb
EFORT Webinar | ORTHOPAEDICS PAEDIATRICS CLINICAL EXAMINATION AND EVALUATION – PART ONE: THE LOWER EXTREMITY
Monday 31 October 2022 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 210 kb
EFORT Webinar | CARTILAGE REPAIR: WHERE WE ARE
Monday 26 September 2022 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 200 kb
EFORT/ESTES Joint Webinar | FLOATING HIP
Monday 13 June 2022 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 180kb
EFORT Webinar | ALIGNMENT GOALS IN TOTAL KNEE ARTHROPLASTY
Monday 30 May 2022 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 180kb
EFORT Webinar Special Edition
MEDICAL AND HUMANITARIAN DISASTER: ORTHOPAEDICS & TRAUMA IN UKRAINE
Monday 16 May 2022 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 160kb
Do you wish to help or would like to get in touch? Please contact: orthopedic.ukraine@gmail.com
EFORT Webinar | RECENT ASPECTS OF DIAGNOSIS AND TREATMENT OF PJI
Monday 25 April 2022 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 180kb
EFORT Webinar | DISTAL FEMUR FRACTURES: RECONSTRUCTION OR REPLACE?
Monday 28 March 2022 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 180kb
EFORT Webinar | TOTAL ANKLE REPLACEMENT: ENHANCING INDICATIONS AND OUTCOMES
Monday 28 February 2022 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 210kb
EFORT Webinar | RELEVANCE OF METAL CARCINOGENICITY FOR ORTOPAEDICS: CONTROVERSIES AND CONCERNS
Monday 31 January 2022 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 220kb
EFORT WEBINARS 2021
AVAILABLE ONLINE REPLAYS
EFORT Webinar | 3D PRINTED RECONSTRUCTIONS IN COMPLEX PELVIC REVISIONS AND ONCOLOGY SURGERY
Monday 29 November 2021 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 490kb
Chair: Pietro Ruggieri | Italy
EFORT Webinar | TOTAL HIP REPLACEMENT AND LUMBAR SPINE
Monday 25 October 2021 | Webinar REPLAY available
More information:
- Scientific Programme & Faculty | PDF Document | 1 page | 650kb
EFORT Webinar | PERIPROSTHETIC FRACTURES OF THE FEMUR (HIP)
Monday 27 September 2021 | Webinar REPLAY available
More information:
- Scientific Programme & Faculty | PDF Document | 1 page | 650kb
EFORT Webinar | ACL-INJURIES IN CHILDREN & ADOLESCENTS WITH OPEN PHYSIS
Monday 14 June 2021 | Webinar REPLAY available
More information:
- Scientific Programme & Faculty | PDF Document | 1 page | 220kb
EFORT Webinar | ELBOW INJURIES
Monday 31 May 2021 | Webinar REPLAY available
More information:
- Scientific Programme & Faculty | PDF Document | 1 page | 215kb
EFORT Webinar | OSTEOTOMIES ABOUT THE KNEE
Monday 26 April 2021 | Webinar REPLAY available
More information
- Scientific Programme & Faculty | PDF Document | 1 page | 210kb
EFORT Webinar | PILON FRACTURES: CURRENT INSIGHTS IN THEIR MANAGEMENT
Monday 29 March 2021 | Webinar REPLAY Available
More information
- Scientific Programme & faculty | PDF Document | 1 page | 135kb
EFORT Webinar | FLATFOOT IN CHILDHOOD
Monday 22 February 2021 | Webinar REPLAY Available
More information
- Scientific Programme & faculty | PDF Document | 1 page | 135kb
EFORT Webinar | PRACTICAL APPLICATION OF ARTIFICIAL INTELLIGENCE
Monday 25 January 20210 | Webinar REPLAY available
More information
- Scientific Programme & faculty | PDF Document | 1 page | 170kb
EFORT WEBINARS 2020
AVAILABLE ONLINE REPLAYS
EFORT/SECEC Webinar | ROTATOR CUFF REPAIR: WHEN AND HOW?
Monday 30 November 2020 | Webinar REPLAY available
A joint collaboration between European Federation of National Associations of Orthopaedics and Traumatology (EFORT) and the European Society for Surgery of the Shoulder and Elbow (SECEC).
More information
- Scientific Programme & faculty | PDF Document | 1 page | 510kb
EFORT Webinar | BONE METASTASES: PRINCIPLES OF A MODERN TREATMENT
Monday 28 September 2020 | Webinar REPLAY available
More information
- Scientific Programme, faculty & related assets | PDF Document | 2 pages | 380kb
EFORT Webinar | NON-INFECTED PAINFUL TOTAL KNEE ARTHROPLASTY
Monday 06 July 2020 | Webinar REPLAY available
More information
- Scientific programme and faculty | PDF document | 1 page | 310 kb
EFORT Webinar | NON-INFECTED PAINFUL TOTAL HIP ARTHROPLASTY
Monday 08 June 2020 | Webinar REPLAY available
More information
- Scientific programme, faculty & related assets | PDF document | 2 pages | 570 kb
EFORT Webinar Special Edition 2 | CO-EXISTING WITH COVID-19 – ELECTIVE ORTHOPAEDIC SURGERY: WHEN & HOW?
Monday 11 May 2020 | Webinar REPLAY available
More information
- Scientific programme & faculty | PDF document | 1 page | 195kb
- Other related webinar REPLAY: Orthopaedic & Trauma Surgeons in time of COVID-19
EFORT Webinar | FAST-TRACK IN JOINT REPLACEMENT
Monday 27 April 2020 | Webinar REPLAY available
More Information
- Scientific programme, faculty and related assets | PDF document | 2 pages | 440kb
EFORT Webinar Special Edition | ORTHOPAEDIC & TRAUMA SURGEONS IN TIME OF COVID-19
Monday 6 April 2020 | Webinar REPLAY available
More Information
- Scientific programme & faculty | PDF document | 1 page | 360kb
EFORT WEBINARS 2019
AVAILABLE ONLINE REPLAYS
EFORT Webinar | SEQUELAE OF CALCANEAL FRACTURES
Monday 25 November 2019 | Webinar REPLAY available
More information
- Scientific programme & related assets | PDF document | 2 pages | 175kb
EFORT Webinar | SURGICAL TREATMENT OF LUMBAR DISK HERNIATION
Monday 28 October 2019 | Webinar REPLAY available
More information
- Scientific programme and additional assets | PDF document | 2 pages | 530kb
EFORT Webinar | ANTERIOR SHOULDER INSTABILITY: TREATMENT OPTIONS
Monday 30 September 2019 | Webinar REPLAY available
More information
- Faculty, scientific programme & related resources |PDF document | 2 pages | 555kb
EFORT Webinar | HOW TO WRITE AN ARTICLE AND GET IT PUBLISHED
Monday 24 June 2019 | Webinar REPLAY available
More information
- Faculty, scientific programme & additional assets | PDF document | 2 pages | 550kb
EFORT Webinar | PATELLOFEMORAL INSTABILITY IN CHILDREN
Monday 27 May 2019 | Webinar REPLAY available
More information
- Faculty, scientific programme & additional assets | PDF document | 2 pages | 380kb
EFORT Webinar | ONE-STAGE VS. TWO-STAGE IN HIP INFECTION: TIPS & TRICKS
Monday 29 April 2019 | Webinar REPLAY available
More information
- Faculty, Scientific Programme & Related Assets | PDF document | 3 pages | 280kb
EFORT Webinar | ADVERSE REACTION TO IMPLANT MATERIALS
Monday 21 January 2019 | Webinar REPLAY available
More information
- Faculty, Scientific Programme & Related Assets | PDF document | 3 pages | 425kb
2018 EFORT WEBINARS
AVAILABLE ONLINE REPLAYS
EFORT Webinar | ADULT SPINE DEFORMITY
Monday 19 November 2018 | Webinar REPLAY available
More information
- Faculty, Scientific Programme & Related Assets | PDF document | 1 page | 485kb
EFORT-SECEC Webinar | FOCUS PROXIMAL HUMERAL FRACTURES
Saturday 20 January 2018 | Webinar REPLAY available
More information
- Faculty, Scientific Programme & Related Assets | PDF document | 1 page | 375kb
2017 EFORT WEBINARS
AVAILABLE ONLINE REPLAYS
EFORT Webinar | TREATMENT OPTIONS OF UNICONDYLAR KNEE OSTEOARTHRITIS IN THE YOUNG ADULT
Tuesday 07 November 2017 | Webinar REPLAY available in VuMedi
More information
- Faculty, Scientific Programme & Related Assets | PDF document | 2 pages | 387kb
- Online REPLAY: https://www.vumedi.com/accounts/login/
EFORT-SOFCOT Webinar | UPDATE IN THE MANAGEMENT OF LOWER EXTREMITY BONE DEFECTS
Saturday 07 October 2017 | NO Webinar REPLAY available
More information
- Faculty, Scientific Programme & Related Assets | PDF Document | 2 pages | 365kb
- Online REPLAY non available
